CellDx Tissue CellDx Tissue

Uncovering Deeper Tumor Insights to Enable Smarter Treatment Decisions

Comprehensive Multi-Omics Profiling for Precision Oncology

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Overview

Proxceq™ is a one-of-a-kind, tissue-based tumor profiling solution designed to provide a deeper understanding of each patient’s cancer and support more personalized treatment strategies. By integrating multiple layers of molecular insight into a single analysis, it helps uncover key biological drivers, identify relevant therapeutic opportunities, and reveal pathways influencing treatment response. This holistic approach goes beyond conventional testing, enabling more informed clinical decisions and expanding the potential for tailored cancer care.

The Proxceq™ Advantage

True Multi-Dimensional Profiling

Simultaneous integration of genomic alterations, gene expression, and protein-level biomarkers

Whole Transcriptome Advantage

Expression analysis across 20,802 genes enables pathway-level insights not captured by standard panels

Single-Test Comprehensive Insight

Eliminates the need for multiple sequential tests, reducing time and tissue requirements

Built for Advanced Oncology Decision Making

Turning Complex Tumor Data into Meaningful Clinical Insight

Individualized Treatment Direction

Align therapy strategies with the unique 
biology of each tumor.

Deeper Biological Understanding

Capture a broader view of tumor mechanisms beyond surface-level alterations

Access to Emerging Options

Identify opportunities across targeted therapies, immunotherapies, and clinical trials

Streamlined Insights

Receive consolidated, easy-to-interpret outputs for faster clinical action

Redefining Multi-Omics Cancer Profiling

Greater Depth. Wider Perspective. Clearer Answers.

Holistic Tumor Assessment

Simultaneously evaluates multiple molecular dimensions for a more complete picture

Expression-Driven Insights

Reveals pathway activity and tumor behavior through gene expression analysis

Enhanced Alteration Detection

Improves identification of clinically relevant 
molecular events through integrated analysis

Unified Interpretation

Delivers a cohesive report combining diverse biomarker insights into a single framework

Supporting Decisions Across the Treatment Journey 

From Initial Diagnosis to Advanced Disease 

Therapy Selection Support

Highlights potential treatment approaches 
aligned with tumor biology

Management of Resistant Disease

Identifies alternative mechanisms and 
pathways in refractory settings

Understanding Treatment Failure

Provides insights into why therapies may lose effectiveness over time

Immunotherapy Consideration

Supports evaluation of suitability for 
immunotherapy-based approaches

Clinical Trial Navigation

Facilitates matching to relevant 
investigational therapies

Multi-Biomarker Evaluation

Comprehensive Molecular Assessment in a Single Test

Tumor DNA Analysis (511 Genes)

Detection of SNVs, InDels, and copy number alterations (CNAs)

RNA-Based Fusion Analysis (51 Genes)

Identification of gene fusions and rearrangements

Gene Expression Profiling (20,802 Genes)

Whole transcriptome analysis enabling pathway-level insights

Tumor Mutational Burden (TMB)

Assessment of overall mutational load to support immunotherapy decisions

Homologous Recombination Deficiency (HRD) Status

Identification of DNA repair deficiencies relevant for targeted therapies

Mismatch Repair Deficiency (dMMR) / Microsatellite Instability (MSI)

Evaluation of genomic instability markers

PD-L1 Expression (IHC-based)

Protein-level assessment to guide immunotherapy selection

Additional Therapy-Relevant IHC Markers

Included as applicable based on tumor type

Clinical Utility Clinical Utility

Why Integrated Multi-Omics Matters

Cancer is driven by complex and interconnected biological processes that cannot always be captured through a single layer of testing. Proxceq™ addresses this by combining multiple molecular dimensions, enabling a more complete understanding of tumor behavior. This integrated approach enhances the ability to identify actionable insights, uncover hidden therapeutic opportunities, and better stratify patients—particularly in complex or advanced disease settings.

From Sample to Insight: The Proxceq™ Workflow

Sample Collection

Tumor tissue (FFPE or fresh biopsy) collected for analysis

Nucleic Acid Preparation

High-quality extraction enabling multi-layered profiling

Comprehensive Analysis

Simultaneous evaluation across multiple molecular dimensions

Data Integration

Advanced analytics translate findings into clinically relevant insights

Actionable Reporting

Clear, prioritized outputs to guide personalized treatment decisions

Frequently Asked Questions

Why is multi-omics profiling important in cancer care?
Cancer is driven by complex biological processes that may not be fully captured by a single type of analysis. Multi-omics profiling combines different molecular layers to provide a more complete understanding of tumor behavior, enabling more informed treatment selection.
What can be expected from a Proxceq™ report?
The report provides a consolidated view of clinically relevant findings, including actionable alterations, biomarker status, pathway insights, and potential therapy options, along with information on relevant clinical trials.
How is Proxceq™ different from conventional genomic tests?
Unlike standard tests that focus only on DNA alterations, Proxceq™ integrates genomic, transcriptomic, and biomarker data, offering deeper biological insight and expanded opportunities for targeted and personalized therapies.
What type of sample is required?
Proxceq™ is performed on tumor tissue samples, including FFPE blocks or fresh biopsy specimens with adequate tumor content.
Which cancer types is Proxceq suitable for?
The test can be applied across a wide range of solid tumors where tissue samples are available, particularly in cases where deeper molecular understanding may impact treatment decisions.
What is the turnaround time (TAT)?
Results are typically available within 5–7 business days from receipt of the sample, depending on sample quality and completeness of clinical information.
Is Proxceq™ performed in an accredited laboratory?
Yes, Proxceq is conducted in a certified laboratory environment following established quality standards.
How are results delivered?
Results are provided as a structured, easy-to-interpret report designed to support clinical decision-making.
How can I access the test results?
Reports are shared securely with the requesting clinician or institution through designated communication channels.
Who can I contact for support or queries?
For test ordering, sample requirements, or report-related queries, please contact our support team or your designated representative. Alternatively, you may reach us at: Email: [email protected]
WhatsApp (Message only): +91 8806150150

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